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Merck

COL6A3

collagen, type VI, alpha 3

동의어:
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UniProtKB ID:
Clone ID:
  • Human(1293) Summary: This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described. [provided by RefSeq, Jun 2009]
  • Mouse(12835) collagen, type VI, alpha 3
  • Rat(367313) collagen, type VI, alpha 3
  • dog(403582) collagen, type VI, alpha 3
  • chicken(396548) collagen, type VI, alpha 3
  • domestic guinea pig(100716662) collagen, type VI, alpha 3
  • cow(530657) collagen, type VI, alpha 3
  • naked mole-rat(101717072) collagen, type VI, alpha 3
  • Zebrafish(556874) collagen, type VI, alpha 3
  • domestic cat(101081323) collagen, type VI, alpha 3

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-COL6A3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-Collagen Type VI Antibody, clone 3C4, ascites fluid, clone 3C4, Chemicon®,
종별 반응성
human
응용분야
electron microscopy
flow cytometry

immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)
Anti-Collagen VI α3 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse
응용분야
ELISA
immunofluorescence

immunohistochemistry
Anti-Collagen VI α3 Antibody, clone 1D6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, mouse, rat
응용분야
affinity binding assay
immunofluorescence

immunohistochemistry

western blot
Anti-Collagen VI α3 Antibody, clone 3C4 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human
응용분야
immunocytochemistry
immunofluorescence

immunohistochemistry

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Col6a3,
mouse
MISSION® esiRNA, targeting human COL6A3,
human