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Merck

CHRM4

cholinergic receptor, muscarinic 4

동의어:
HM4, M4R
종:
Human CHRM4 (1132), Mouse Chrm4 (12672), Rat Chrm4 (25111), domestic guinea pig Chrm4 (100714736), naked mole-rat Chrm4 (101726411), Domestic Rabbit CHRM4 (100008791), dog CHRM4 (611314), cow CHRM4 (512928), sheep CHRM4 (101114554), domestic cat CHRM4 (101088360)
UniProtKB ID:
P08173, B2RPP4, Q0VD60, Q4VBK7
Clone ID:
  • Human(1132) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
  • Mouse(12672) cholinergic receptor, muscarinic 4
  • Rat(25111) cholinergic receptor, muscarinic 4
  • domestic guinea pig(100714736) cholinergic receptor, muscarinic 4
  • naked mole-rat(101726411) cholinergic receptor, muscarinic 4
  • Domestic Rabbit(100008791) cholinergic receptor, muscarinic 4
  • dog(611314) cholinergic receptor, muscarinic 4
  • cow(512928) cholinergic receptor, muscarinic 4
  • sheep(101114554) cholinergic receptor, muscarinic 4
  • domestic cat(101088360) cholinergic receptor, muscarinic 4
  • chicken(423195) cholinergic receptor, muscarinic 4

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Small Molecule - Agonist

제품 번호
설명
종
P6628
Pilocarpine nitrate salt, ≥98% (HPLC),
종
human
A2251
Acetyl-β-methylcholine chloride, ≥98% (TLC), powder,
종
human
P6503
Pilocarpine hydrochloride, ≥99% (titration), powder,
종
human
O100
Oxotremorine M, solid,
종
human
M104
(±)-Muscarine chloride hydrate, ≥98% (HPLC),
종
human

Small Molecule - Antagonist

제품 번호
설명
종
B1390
Bisacodyl, analytical standard, for drug analysis,
종
human
T9778
Tropicamide, solid,
종
human
O2881
Oxybutynin chloride, ≥98% (TLC), powder,
종
human
P8891
Propantheline bromide, ≥97% (TLC), powder,
종
human
S7882
(−)-Scopolamine N-butyl bromide, ≥98% (TLC), powder,
종
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
ZMS1165
Anti-CHRM4 Antibody, clone 18C7.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human
응용분야
ELISA
affinity binding assay
immunocytochemistry
western blot
MAB1578
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2, clone 18C7.2, Chemicon®, from mouse,
종별 반응성
monkey
응용분야
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB4300824
Anti-CHRM4 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot
MAB1576
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2, purified antibody, clone 17F10.2, Chemicon®,
종별 반응성
monkey, mouse, rat
응용분야
immunocytochemistry
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

제품 번호
설명
종
A8404
Amitriptyline hydrochloride, ≥98% (TLC), powder,
종
human
D4526
Doxepin hydrochloride, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
종
human
51330
Harmaline, ≥95%,
종
human, rat

Small Molecule - Ligand

제품 번호
설명
종
A138
Aminobenztropine, solid,
종
human

esiRNA

제품 번호
설명
종
EMU046221
MISSION® esiRNA, targeting mouse Chrm4,
종
mouse