CASP5
caspase 5, apoptosis-related cysteine peptidase
동의어:
ICE(rel)III, ICEREL-III, ICH-3
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UniProtKB ID:
Clone ID:
- Human(838) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
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Antibodies
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Anti Caspase 5 Antibody, clone 23GB3315, Rabbit Monoclonal, clone 23GB3315, recombinant rabbit monoclonal, expressed in HEK293 cells,
종별 반응성
human, rat
응용분야
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Caspase-5 Antibody, from rabbit, purified by affinity chromatography,
종별 반응성
human
응용분야
immunocytochemistry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-CASP5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Proteins
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esiRNA
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