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Merck

CAPN6

calpain 6

동의어:
CANPX, CAPNX, CalpM, DJ914P14.1
:
UniProtKB ID:
Clone ID:
  • Human(827) Summary: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. [provided by RefSeq, Nov 2009]
  • Mouse(12338) calpain 6
  • Rat(83685) calpain 6
  • dog(492068) calpain 6
  • chicken(422341) calpain 6
  • naked mole-rat(101712448) calpain 6
  • domestic guinea pig(100720507) calpain 6
  • sheep(101110122) calpain 6
  • Domestic Rabbit(100348781) calpain 6
  • domestic cat(101095474) calpain 6
  • Horse(100054264) calpain 6
  • cow(539360) calpain 6

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-CAPN6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-CAPN6 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
응용분야
immunofluorescence
immunohistochemistry

western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Capn6,
mouse
MISSION® esiRNA, targeting human CAPN6,
human