BRCA2
breast cancer 2, early onset
동의어:
BRCC2, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1, GLM3, PNCA2
종:
Human BRCA2 (675), Mouse Brca2 (12190), Rat Brca2 (360254), domestic guinea pig Brca2 (100713136), Zebrafish brca2 (566758), naked mole-rat Brca2 (101698015), chicken BRCA2 (374139), sheep BRCA2 (101109980), fruit fly Brca2 (37916), cow BRCA2 (507069) ...더
UniProtKB ID:
Clone ID:
- Human(675) Summary: Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008]
- Mouse(12190) breast cancer 2
- Rat(360254) breast cancer 2, early onset
- domestic guinea pig(100713136) breast cancer 2, early onset
- Zebrafish(566758) breast cancer 2, early onset
- naked mole-rat(101698015) breast cancer 2, early onset
- chicken(374139) breast cancer 2, early onset
- sheep(101109980) breast cancer 2, early onset
- fruit fly(37916) Breast cancer 2, early onset homolog
- cow(507069) breast cancer 2, early onset
- dog(474180) breast cancer 2, early onset
- domestic cat(493878) breast cancer 2, early onset
- Horse(100064578) breast cancer 2, early onset
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Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-BRCA2 Antibody, clone 5.23, clone 5.23, Upstate®, from mouse,
종별 반응성
human
응용분야
immunocytochemistry
western blot
western blot
Monoclonal Anti-BRCA2 antibody produced in mouse, clone 3D12, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
western blot
Anti-BRCA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
Anti-BRCA2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, rat
응용분야
ELISA
immunohistochemistry
immunohistochemistry