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Merck

BMPR2

bone morphogenetic protein receptor, type II (serine/threonine kinase)

동의어:
BMPR-II, BMPR3, BMR2, BRK-3, PPH1, T-ALK
:
UniProtKB ID:
Clone ID:
  • Human(659) Summary: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
  • Mouse(12168) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • Rat(140590) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • cow(407127) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • naked mole-rat(101701138) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • Domestic Rabbit(100350246) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • sheep(101103793) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • domestic guinea pig(100736232) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • chicken(374147) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • sheep(100294556) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • domestic cat(101096338) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • dog(478875) bone morphogenetic protein receptor, type II (serine/threonine kinase)

Custom & Knockdown Gene Products

ELISA

제품 번호
설명
Human BMPR-II ELISA Kit, for cell culture supernatants, plasma, and serum samples,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Monoclonal Anti-BMPR2 antibody produced in mouse, clone 4A2, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
Monoclonal Anti-BMPR2 antibody produced in mouse, clone 3F6, ascites fluid,
종별 반응성
human, monkey, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-BMR2 Antibody, clone 3F6, ascites fluid, clone 3F6, from mouse,
종별 반응성
human, monkey, mouse, rat
응용분야
immunofluorescence
immunohistochemistry

western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human BMPR2,
human
MISSION® esiRNA, targeting mouse Bmpr2,
mouse