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Merck

ATP1A1

ATPase, Na+/K+ transporting, alpha 1 polypeptide

동의어:
:
UniProtKB ID:
Clone ID:
  • Human(476) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
  • Mouse(11928) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Rat(24211) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • domestic cat(101083695) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Horse(100034139) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • dog(403992) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • chicken(396530) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Domestic Rabbit(100302415) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • sheep(443381) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • cow(282144) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • naked mole-rat(101697634) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • domestic guinea pig(100192382) ATPase, Na+/K+ transporting, alpha 1 polypeptide

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Small Molecule - Activator

제품 번호
설명
Digitoxigenin, ,
rat

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-Na+/K+ ATPase (α Subunit) antibody produced in mouse, clone M7-PB-E9, ascites fluid,
종별 반응성
bovine, canine, chicken, human, mouse, pig, sheep
응용분야
ELISA
immunocytochemistry

immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-phospho-ATP1 α1/Na+K+ ATPase1 (pSer23) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

western blot
Anti-ATP1 α antibody produced in rabbit, affinity isolated antibody,
종별 반응성
rat
응용분야
ELISA
immunofluorescence

western blot
Anti-ATPASE antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
xenopus, canine, human, monkey, mouse, porcine, rabbit, rat, sheep
응용분야
immunocytochemistry
immunohistochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
Melittin, ≥97% (HPLC), synthetic,
mouse, rat, human
Digoxin, analytical standard,
human
Digoxin, United States Pharmacopeia (USP) Reference Standard,
human
Digitoxin for LC assay, European Pharmacopoeia (EP) Reference Standard,
human
Digoxin, European Pharmacopoeia (EP) Reference Standard,
human

Proteins

제품 번호
설명
Adenosine 5′-Triphosphatase from porcine cerebral cortex, lyophilized powder, ≥0.3 units/mg protein, pH 7.8,

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Atp1a1,
mouse
MISSION® esiRNA, targeting human ATP1A1,
human