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Merck

APBB1

amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)

동의어:
FE65, MGC:9072, RIR
:
UniProtKB ID:
Clone ID:
  • Human(322) Summary: The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
  • Mouse(11785) amyloid beta (A4) precursor protein-binding, family B, member 1
  • Rat(29722) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • naked mole-rat(101699658) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • domestic cat(101090045) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • domestic guinea pig(100735070) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • cow(505096) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • Domestic Rabbit(100354159) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • dog(476833) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • chicken(100859045) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • Horse(100069964) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • Zebrafish(565164) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
KD-Validated Anti APBB1 Antibody, clone 23GB3665, Rabbit Monoclonal, clone 23GB3665, recombinant rabbit monoclonal, expressed in HEK293 cells,
종별 반응성
human
응용분야
flow cytometry
immunofluorescence

western blot
Anti-APBB1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
western blot
Anti-APBB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-APBB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
Anti-Fe65 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
mouse
응용분야
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human APBB1,
human
MISSION® esiRNA, targeting mouse Apbb1,
mouse