์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
Merck

AIRE

autoimmune regulator

๋™์˜์–ด:
AIRE1, APECED, APS1, APSI, PGA1
์ข…:
Human AIRE (326), Mouse Aire (11634), Rat Aire (294328), domestic guinea pig Aire (100729880), sheep AIRE (101102698), cow AIRE (784775), Zebrafish aire (100007662), chicken AIRE (429666), dog AIRE (487796), naked mole-rat Aire (101725873)
UniProtKB ID:
O43918, B2RP50, O43922, O43932, O75745
Clone ID:
  • Human(326) Summary: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
  • Mouse(11634) autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
  • Rat(294328) autoimmune regulator
  • domestic guinea pig(100729880) autoimmune regulator
  • sheep(101102698) autoimmune regulator
  • cow(784775) autoimmune regulator
  • Zebrafish(100007662) autoimmune regulator
  • chicken(429666) autoimmune regulator
  • dog(487796) autoimmune regulator
  • naked mole-rat(101725873) autoimmune regulator
  • domestic cat(101091039) autoimmune regulator

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
์‘์šฉ๋ถ„์•ผ
SAB2500046
Anti-AIRE (Isoforms 1 and 2) (AB1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human, mouse
์‘์šฉ๋ถ„์•ผ
ChIP
ELISA
western blot
09-456
Anti-AIRE Antibody, Upstateยฎ, from rabbit,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
mouse
์‘์šฉ๋ถ„์•ผ
western blot
SAB4501439
Anti-AIRE antibody produced in rabbit, affinity isolated antibody,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human
์‘์šฉ๋ถ„์•ผ
ELISA
western blot
SAB2500045
Anti-AIRE (Isoform 1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
bovine, canine, human, rat
์‘์šฉ๋ถ„์•ผ
ELISA
immunohistochemistry
western blot
SAB2500047
Anti-AIRE (Isoforms 1 and 2) (AB2) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human
์‘์šฉ๋ถ„์•ผ
ELISA
immunohistochemistry
western blot

esiRNA

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…
EMU030981
MISSIONยฎ esiRNA, targeting mouse Aire,
์ข…
mouse
EHU151501
MISSIONยฎ esiRNA, targeting human AIRE,
์ข…
human