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Merck

AIRE

autoimmune regulator

동의어:
AIRE1, APECED, APS1, APSI, PGA1
종:
UniProtKB ID:
Clone ID:
  • Human(326) Summary: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
  • Mouse(11634) autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
  • Rat(294328) autoimmune regulator
  • domestic guinea pig(100729880) autoimmune regulator
  • sheep(101102698) autoimmune regulator
  • cow(784775) autoimmune regulator
  • Zebrafish(100007662) autoimmune regulator
  • chicken(429666) autoimmune regulator
  • dog(487796) autoimmune regulator
  • naked mole-rat(101725873) autoimmune regulator
  • domestic cat(101091039) autoimmune regulator

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-AIRE (Isoform 1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
bovine, canine, human, rat
응용분야
ELISA
immunohistochemistry

western blot
Anti-AIRE (Isoforms 1 and 2) (AB2) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunohistochemistry

western blot
Anti-AIRE antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
western blot
Anti-AIRE Antibody, Upstate®, from rabbit,
종별 반응성
mouse
응용분야
western blot
Anti-AIRE (Isoforms 1 and 2) (AB1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse
응용분야
ChIP
ELISA

western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human AIRE,
human
MISSION® esiRNA, targeting mouse Aire,
mouse