ACLY
ATP citrate lyase
동의어:
ACL, ATPCL, CLATP
종:
Human ACLY (47), Mouse Acly (104112), Rat Acly (24159), chicken ACLY (395373), naked mole-rat Acly (101700349), domestic guinea pig Acly (100714933), dog ACLY (607852), Horse ACLY (100053195), domestic cat ACLY (100422779), cow ACLY (511135)
UniProtKB ID:
Clone ID:
- Human(47) Summary: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(104112) ATP citrate lyase
- Rat(24159) ATP citrate lyase
- chicken(395373) ATP citrate lyase
- naked mole-rat(101700349) ATP citrate lyase
- domestic guinea pig(100714933) ATP citrate lyase
- dog(607852) ATP citrate lyase
- Horse(100053195) ATP citrate lyase
- domestic cat(100422779) ATP citrate lyase
- cow(511135) ATP citrate lyase
- sheep(654404) ATP citrate lyase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-ACLY Antibody, clone 8A0V0, Rabbit Monoclonal, ,
종별 반응성
human, rat
응용분야
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Phospho-ACLY-S455 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-ACLY Antibody, clone 1B16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, mouse, rat
응용분야
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-ATP-Citrate Lyase antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot
western blot
Anti-phospho-ATP-Citrate Lyase (pSer454) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
제품 번호
설명
종
ATP Citrate Lyase Active human, recombinant, expressed in baculovirus, ≥90% (SDS-PAGE),
종
human