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Merck

AANAT

aralkylamine N-acetyltransferase

동의어:
DSPS, SNAT
:
UniProtKB ID:
Clone ID:
  • Human(15) Summary: The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  • Mouse(11298) arylalkylamine N-acetyltransferase
  • Rat(25120) aralkylamine N-acetyltransferase
  • chicken(396066) aralkylamine N-acetyltransferase
  • sheep(443531) aralkylamine N-acetyltransferase
  • domestic guinea pig(100724241) aralkylamine N-acetyltransferase
  • domestic cat(101098178) aralkylamine N-acetyltransferase
  • dog(483331) aralkylamine N-acetyltransferase
  • Goat(100860947) aralkylamine N-acetyltransferase
  • cow(281583) arylalkylamine N-acetyltransferase
  • naked mole-rat(101713893) aralkylamine N-acetyltransferase

Custom & Knockdown Gene Products

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-phospho-Serotonin N-Acetyltransferase (N-Terminal) (pThr29) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
rat
응용분야
western blot
ANTI-AANAT (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
종별 반응성
human
응용분야
western blot
Anti-AANAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Anti-AANAT Antibody, serum, Chemicon®,
종별 반응성
bovine, fish, human, rat, sheep
응용분야
western blot
Anti-Serotonin N-Acetyltransferase (C-Terminal) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
mouse, rat
응용분야
western blot