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  • [An increase in the radioprotective effect of O-methyltyramine and mezaton by monoamine oxidase inhibitors].

[An increase in the radioprotective effect of O-methyltyramine and mezaton by monoamine oxidase inhibitors].

Radiobiologiia (1993-01-01)
V I Kulinskiĭ, V Z Gorkin, A D Klimova, N P Rumiantseva
ABSTRACT

Specific 2-propynylamine inhibitors of monoamine oxidase (MAO) pargyline and especially chlorgyline, a selective inhibitor of MAO A (but not deprenyl, a selective inhibitor of MAO B) increase the radioprotective effect of small doses of O-methyltyramine and phenylephrine and do not change the efficacy of large doses. This is consistent with the receptor theory of the mechanism of protective action of amines.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
4-Methoxyphenethylamine, ≥98%