- [An increase in the radioprotective effect of O-methyltyramine and mezaton by monoamine oxidase inhibitors].
[An increase in the radioprotective effect of O-methyltyramine and mezaton by monoamine oxidase inhibitors].
Radiobiologiia (1993-01-01)
V I Kulinskiĭ, V Z Gorkin, A D Klimova, N P Rumiantseva
PMID8469735
ABSTRACT
Specific 2-propynylamine inhibitors of monoamine oxidase (MAO) pargyline and especially chlorgyline, a selective inhibitor of MAO A (but not deprenyl, a selective inhibitor of MAO B) increase the radioprotective effect of small doses of O-methyltyramine and phenylephrine and do not change the efficacy of large doses. This is consistent with the receptor theory of the mechanism of protective action of amines.
MATERIALS