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Key Documents

SML3431

Sigma-Aldrich

JBSNF-000088

≥98% (HPLC)

Synonym(s):

6-Methoxy-3-pyridinecarboxamide, 6-Methoxyniacinamide, 6-Methoxynicotinamide, NSC 70628

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About This Item

Empirical Formula (Hill Notation):
C7H8N2O2
CAS Number:
7150-23-4
Molecular Weight:
152.15
MDL number:
MFCD00229166
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

InChI

1S/C7H8N2O2/c1-11-6-3-2-5(4-9-6)7(8)10/h2-4H,1H3,(H2,8,10)

InChI key

KXDSMFBEVSJYRF-UHFFFAOYSA-N

Biochem/physiol Actions

JBSNF-000088 is a cell penetrant, potent and selective inhibitor of Nicotinamide N-methyltransferase (NNMT) that reduces 1-methyl-nicotinamide (MNA) and improved glucose control in mice models of metabolic disease. JBSNF-000088 potently inhibits growth of PFA ependymoma cells.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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