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E6515

Sigma-Aldrich

Methionine Enkephalin-Arg-Gly-Leu

≥97% (HPLC)

Synonym(s):

MERGL, Tyr-Gly-Gly-Phe-Met-Arg-Gly-Leu

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About This Item

Empirical Formula (Hill Notation):
C41H61N11O10S
CAS Number:
Molecular Weight:
900.06
UNSPSC Code:
12352200

Assay

≥97% (HPLC)

storage temp.

−20°C

Preparation Note

Originally extracted from bovine adrenal medulla

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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P A Steele et al.
Cell and tissue research, 284(2), 331-339 (1996-05-01)
Research has suggested that exogenous opioid substances can have direct effects on cardiac muscle or influence neurotransmitter release via presynaptic modulation of neuronal inputs to the heart. In the present study, multiple-labelling immunohistochemistry was employed to determine the distribution of
T Mimoda et al.
Anatomia, histologia, embryologia, 27(1), 65-69 (1998-03-20)
The duodenum of various ruminants was examined by immunohistochemical staining for serotonin, substance P and Metenkephalin-Arg6-Gly7-Leu8 (MENK8). Serotonin- and substance P-immunoreactive endocrine cells were detected in samples from cow, calf, sheep, goat, and barbary sheep, MENK8-immunoreactive endocrine cells were detected
C Dass
Journal of mass spectrometry : JMS, 31(1), 77-82 (1996-01-01)
Substantial differences were observed in terms of extent of fragmentation and type of ions in the conventional fast atom bombardment (FAB) mass spectra of peptides between different liquid matrices (such as glycerol, thioglycerol, dithiothreitol, thiodiglycol, 3-nitrobenzyl alcohol, diglyme, and sulfolane).
R Magoul et al.
Peptides, 15(5), 883-892 (1994-01-01)
The morphological support of interactions between enkephalins and three systems--beta-endorphin (beta-END), tyrosine hydroxylase (TH), or neuropeptide Y (NPY)--well represented in the arcuate nucleus, was examined by using an electron microscopic double immunostaining combining two sensitive chromogens, diaminobenzidine (DAB) and tetramethylbenzidine
Y K Ng et al.
Annals of the Academy of Medicine, Singapore, 24(6), 793-801 (1995-11-01)
The submandibular ganglion (SMG) of both the rat and monkey is composed of a collection of small ganglia distributed mainly at the hilum of the submandibular gland. Ultrastructurally, its constituent neurons have a prominent nucleus and numerous randomly distributed cytoplasmic

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