Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

75256

Supelco

Synephrine

analytical standard

Synonym(s):

1-(4-Hydroxyphenyl)-2-methylaminoethanol, 4-Hydroxy-α-(methylaminomethyl)benzyl alcohol

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C9H13NO2
CAS Number:
94-07-5
Molecular Weight:
167.21
EC Number:
202-300-9
MDL number:
MFCD00002370
UNSPSC Code:
85151701
PubChem Substance ID:
329766291
NACRES:
NA.24

grade

analytical standard

Assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤12.0% water (Karl Fischer)

application(s)

food and beverages

format

neat

storage temp.

2-8°C

InChI

1S/C9H13NO2/c1-10-6-9(12)7-2-4-8(11)5-3-7/h2-5,9-12H,6H2,1H3

InChI key

YRCWQPVGYLYSOX-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Synephrine is a sympathomimetic amine from the plant Citrus aurantium and is identified as a major active component of dietary supplements.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Synephrine may be used as a reference standard for the determination of synephrine in dietary supplements using high-performance liquid chromatography with acidic potassium permanganate chemiluminescence detection.

Analysis Note

identification (GC-MS): identity conforms

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCH6804
BCCH4739
BCCG9038
BCCG7213
BCCG4406

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Determination of synephrine in weight-loss products using high performance liquid chromatography with acidic potassium permanganate chemiluminescence detection.
Slezak T, et al.
Analytica Chimica Acta, 593(1), 98-102 (2007)
Ischemic stroke associated with use of an ephedra-free dietary supplement containing synephrine.
Bouchard CN, et al.
Mayo Clinic Proceedings. Mayo Clinic, 80(4), 541-545 (2005)
Sidney J Stohs et al.
Phytotherapy research : PTR, 25(10), 1421-1428 (2011-04-12)
Citrus aurantium (bitter orange) extract and its principal protoalkaloidal constituent p-synephrine are widely used in weight loss and weight management as well as in sports performance products. However, questions are raised frequently regarding the safety of these ingredients. The potential
Sidney J Stohs et al.
International journal of medical sciences, 9(7), 527-538 (2012-09-20)
This review summarizes the published as well as unpublished human studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine, providing information and an assessment of the safety and efficacy of these widely used products. The results of
Luciana Grazziotin Rossato et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(1), 8-16 (2010-11-16)
Synephrine is cited as 'the active component' of plants and dietary supplements used in weight loss. It became one of the most popular stimulants present in weight-loss products after the US Food and Drug Administration had interdicted the use of
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service