Skip to Content
Merck
All Photos(2)

Documents

MAB3045

Sigma-Aldrich

Anti-Connexin 35/36 Antibody, clone 8F6.2

clone 8F6.2, Chemicon®, from mouse

Synonym(s):

Cx35/36

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

8F6.2, monoclonal

species reactivity

monkey, fish, rabbit

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

isotype

IgG1

UniProt accession no.

Q8JFD6

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

rabbit ... Gjd2(100341036)

Specificity

Recognizes perch Connexin 35. Does not cross-react with Connexin 34.7, a very closely related protein. Also recognizes rabbit and macaque Connexin 36, the gene homologue of Connexin 35. Labels gap junctions in retinas of perch, rabbit and macaque in immunohistochemistry.

Application

Detect Connexin 35/36 using this Anti-Connexin 35/36 Antibody, clone 8F6.2 validated for use in IH.

Linkage

Replaces: MAB3044

Physical form

Format: Purified
Purified immunoglobulin. Liquid in 0.1M Citrate buffer with 50% glycerol, also contains 0.1% Sodium Azide as a preservative

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Elena Ivanova et al.
Frontiers in cellular neuroscience, 9, 390-390 (2015-10-21)
Retinal degeneration (RD) encompasses a family of diseases that lead to photoreceptor death and visual impairment. Visual decline due to photoreceptor cell loss is further compromised by emerging spontaneous hyperactivity in inner retinal cells. This aberrant activity acts as a
Adam C Miller et al.
eLife, 6 (2017-05-23)
Neural network function is based upon the patterns and types of connections made between neurons. Neuronal synapses are adhesions specialized for communication and they come in two types, chemical and electrical. Communication at chemical synapses occurs via neurotransmitter release whereas
Distribution of the gap junction protein connexin 35 in the central nervous system of developing zebrafish larvae.
Jabeen, S; Thirumalai, V
Frontiers in Neural Circuits null
Shuo Zhang et al.
Investigative ophthalmology & visual science, 61(6), 24-24 (2020-06-13)
The present study tested the hypothesis that connexin-36 (Cx36) and gap junctions between photoreceptor cells contribute to the circadian rhythm of the photopic electroretinogram (ERG) b-wave amplitude. Cone-specific disruption of Cx36 was obtained in mice with a floxed Gjd2 gene
J E Rash et al.
Journal of neurocytology, 33(1), 131-151 (2004-06-03)
Combined confocal microscopy and freeze-fracture replica immunogold labeling (FRIL) were used to examine the connexin identity at electrical synapses in goldfish brain and rat retina, and to test for "co-localization" vs. "close proximity" of connexins to other functionally interacting proteins
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service