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Assay
99%
mp
247-250 °C (lit.)
SMILES string
Cl[H].C1CN(CCN1)c2ccccc2
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 82(1), 383-388 (2011-08-09)
New Hofmann type clathrates in the form of M(pp)(2)Ni(CN)(4)·2G (where pp = 1-phenylpiperazine, G = 1,4-dioxane and M = Ni, Co or Cd) have been prepared in powder form and their FT-IR and FT-Raman spectra are reported. The results suggest
Pharmacological reports : PR, 63(1), 71-78 (2011-03-29)
The present study was designed to investigate the central nervous system activity of 23 novel phenylpiperazine pyrrolidin-2-one derivatives. These compounds had marked antiarrhythmic and hypotensive activities and revealed affinity for α1- and α2-adrenoceptors. These effects may be related to their
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 96, 586-593 (2012-08-07)
With the purpose of evaluating the ability of Pd(II) complex to interact with DNA molecule as the main biological target, two new complexes [Pd(bpy)(OH(2))(2)] (1) and [Pd(Phenpip)(OH(2))(2)] (2), where (bpy=2,2'-bipyridine; Phenpip=1-phenylpiperazine), have been synthesized and the binding properties of these
Bioorganic & medicinal chemistry, 20(7), 2290-2303 (2012-03-03)
An association between α(1)-adrenoceptor affinities, hERG K(+)-antagonistic properties and antiarrhythmic activities for a series of phenylpiperazine derivatives of hydantoin (2a-21a) was investigated. New compounds were synthesized and tested for their affinity for α(1)-adrenoceptors in radioligand binding assay using [(3)H]-prazosin as
Bioorganic & medicinal chemistry, 21(7), 1680-1684 (2013-02-23)
Employing the D4 selective phenylpiperazine 2 as a lead compound, planar chiral analogs with paracyclophane substructure were synthesized and evaluated for their ability to bind and activate dopamine receptors. The study revealed that the introduction of a [2.2]paracyclophane moiety is
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