SNCB
synuclein, beta
- Human(6620) Summary: The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease; however, no direct relation to Parkinson disease has been established. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(104069) synuclein, beta
- Rat(113893) synuclein, beta
- sheep(101106009) synuclein, beta
- cow(508421) synuclein, beta
- domestic cat(101080866) synuclein, beta
- dog(479279) synuclein, beta
- chicken(395391) synuclein, beta
- Zebrafish(393944) synuclein, beta
- naked mole-rat(101708817) synuclein, beta
- domestic guinea pig(100732218) synuclein, beta
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