POU5F1
POU class 5 homeobox 1
- Human(5460) Summary: This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Mar 2010]
- Mouse(18999) POU domain, class 5, transcription factor 1
- Rat(294562) POU class 5 homeobox 1
- sheep(100302349) POU class 5 homeobox 1
- cow(282316) POU class 5 homeobox 1
- domestic cat(100174788) POU class 5 homeobox 1
- dog(481709) POU class 5 homeobox 1
- Goat(100861237) POU class 5 homeobox 1
- domestic guinea pig(100724951) POU class 5 homeobox 1
- Domestic Rabbit(100101567) POU class 5 homeobox 1
- naked mole-rat(101722299) POU class 5 homeobox 1
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