NDRG1
N-myc downstream regulated 1
Synonyms:
CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5
Species:
Human NDRG1 (10397), Mouse Ndrg1 (17988), Rat Ndrg1 (299923), cow NDRG1 (504499), naked mole-rat Ndrg1 (101722001), domestic guinea pig Ndrg1 (100728790), sheep NDRG1 (101120172), domestic cat NDRG1 (101089078), Horse NDRG1 (100068997), dog NDRG1 (482049)
UniProtKB ID:
Gene ID:
- Human(10397) Summary: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
- Mouse(17988) N-myc downstream regulated gene 1
- Rat(299923) N-myc downstream regulated 1
- cow(504499) N-myc downstream regulated 1
- naked mole-rat(101722001) N-myc downstream regulated 1
- domestic guinea pig(100728790) N-myc downstream regulated 1
- sheep(101120172) N-myc downstream regulated 1
- domestic cat(101089078) N-myc downstream regulated 1
- Horse(100068997) N-myc downstream regulated 1
- dog(482049) N-myc downstream regulated 1
- chicken(420321) N-myc downstream regulated 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NDRG1 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, human
Application
western blot
Monoclonal Anti-NDRG1 antibody produced in mouse, clone 2D7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Phospho-NDRG1 (Thr346) Antibody, clone 5N4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, human, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
inhibition assay
western blot
immunocytochemistry
immunohistochemistry
inhibition assay
western blot
Anti-NDRG1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-NDRG1 Antibody, clone 1C11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot