Skip to Content
Merck

MTPN

myotrophin

Synonyms:
GCDP, V-1
Species:
UniProtKB ID:
Gene ID:
  • Human(136319) Summary: The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008]
  • Mouse(14489) myotrophin
  • Rat(79215) myotrophin
  • cow(541099) myotrophin
  • domestic cat(101097881) myotrophin
  • naked mole-rat(101713593) myotrophin
  • dog(403487) myotrophin
  • Zebrafish(406240) myotrophin
  • domestic guinea pig(100718423) myotrophin
  • chicken(395702) myotrophin
  • sheep(101102640) myotrophin

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MTPN antibody produced in mouse, clone 1F3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-MTPN antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-MTPN antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-MTPN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MTPN (2),
Species
human
MISSION® esiRNA, targeting human MTPN,
Species
human
MISSION® esiRNA, targeting mouse Mtpn,
Species
mouse