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Merck

KDM4C

lysine (K)-specific demethylase 4C

Synonyms:
GASC1, JHDM3C, JMJD2C, TDRD14C, bA146B14.1
Species:
UniProtKB ID:
Gene ID:
  • Human(23081) Summary: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
  • Mouse(76804) lysine (K)-specific demethylase 4C
  • Rat(298144) lysine (K)-specific demethylase 4C
  • Horse(100060699) lysine (K)-specific demethylase 4C
  • naked mole-rat(101698040) lysine (K)-specific demethylase 4C
  • dog(474704) lysine (K)-specific demethylase 4C
  • Domestic Rabbit(100343440) lysine (K)-specific demethylase 4C
  • cow(535671) lysine (K)-specific demethylase 4C
  • chicken(427231) lysine (K)-specific demethylase 4C
  • sheep(101117992) lysine (K)-specific demethylase 4C
  • domestic guinea pig(100719980) lysine (K)-specific demethylase 4C
  • domestic cat(101100423) lysine (K)-specific demethylase 4C

Custom & Knockdown Gene Products

  • siRNA

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  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
ANTI-JMJD2C (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
western blot
Anti-KDM4C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human KDM4C, AL513412.1, RP11-146B14.1,
Species
human