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Merck

HTRA4

HtrA serine peptidase 4

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(203100) Summary: This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq, Oct 2008]
  • Mouse(330723) HtrA serine peptidase 4
  • Rat(306564) HtrA serine peptidase 4
  • cow(514946) HtrA serine peptidase 4
  • dog(475580) HtrA serine peptidase 4

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HTRA4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-HTRA4 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-HTRA4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HTRA4,
Species
human
MISSION® esiRNA, targeting mouse Htra4,
Species
mouse