F2
coagulation factor II (thrombin)
Synonyms:
PT, RPRGL2, THPH1
Species:
Human F2 (2147), Mouse F2 (14061), Rat F2 (29251), naked mole-rat F2 (101720561), domestic guinea pig F2 (100725988), sheep F2 (100307041), cow F2 (280685), domestic cat F2 (101090463), dog F2 (100686115), chicken F2 (395306)
UniProtKB ID:
Gene ID:
- Human(2147) Summary: Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq, Jul 2008]
- Mouse(14061) coagulation factor II
- Rat(29251) coagulation factor II
- naked mole-rat(101720561) coagulation factor II (thrombin)
- domestic guinea pig(100725988) coagulation factor II (thrombin)
- sheep(100307041) coagulation factor II (thrombin)
- cow(280685) coagulation factor II (thrombin)
- domestic cat(101090463) coagulation factor II (thrombin)
- dog(100686115) coagulation factor II (thrombin)
- chicken(395306) coagulation factor II (thrombin)
- Zebrafish(325881) coagulation factor II (thrombin)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Thrombin Antibody, clone GMA-020, clone GMA-020, Upstate®, from mouse,
Species Reactivity
human
Application
western blot
Anti-F2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-F2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-THRB (AP2, Cleaved-Arg327) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-Prothrombin Antibody, clone GMA-095, clone GMA-095, Upstate®, from mouse,
Species Reactivity
human
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
Thrombin human, BioUltra, recombinant, expressed in HEK 293 cells, aqueous solution, ≥95% (SDS-PAGE),
Species
human
Thrombin from human plasma, lyophilized powder, ≥2800 NIH units/mg protein (E1%/280, 18.3),
Species
human
esiRNA
Product Number
Description
Species