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Merck

CD3E

CD3e molecule, epsilon (CD3-TCR complex)

Synonyms:
T3E, TCRE
Species:
UniProtKB ID:
Gene ID:
  • Human(916) Summary: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
  • Mouse(12501) CD3 antigen, epsilon polypeptide
  • Rat(315609) CD3 molecule, epsilon
  • domestic cat(493936) CD3e molecule, epsilon (CD3-TCR complex)
  • naked mole-rat(101711464) CD3e molecule, epsilon (CD3-TCR complex)
  • dog(442981) CD3e molecule, epsilon (CD3-TCR complex)
  • sheep(443437) CD3e molecule, epsilon (CD3-TCR complex)
  • Domestic Rabbit(100008616) CD3e molecule, epsilon (CD3-TCR complex)
  • domestic guinea pig(100727781) CD3e molecule, epsilon (CD3-TCR complex)
  • cow(281054) CD3e molecule, epsilon (CD3-TCR complex)
  • chicken(396062) CD3e molecule, epsilon (CD3-TCR complex)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CD3E antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CD3E antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-CD3-APC antibody produced in mouse, clone APA1/1,
Species Reactivity
Application
flow cytometry
Monoclonal Anti-CD3-APC antibody produced in mouse, clone OKT3,
Species Reactivity
Application
flow cytometry
Anti-CD3E antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM344, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cd3e,
Species
mouse
MISSION® esiRNA, targeting human CD3E,
Species
human