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Merck

ASAH2

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

Synonyms:
BCDase, HNAC1, LCDase, N-CDase, NCDase
Species:
Human ASAH2 (56624), Mouse Asah2 (54447), Rat Asah2 (114104), cow ASAH2 (615837), cow ASAH2 (100336736), sheep ASAH2 (101121732), Horse ASAH2 (100071829), domestic cat ASAH2 (101097670), dog ASAH2 (486461), chicken ASAH2 (423679) ...More
UniProtKB ID:
Q9NR71, Q3KNU1, Q5SNT7, Q5SZP6, Q5SZP7, Q5T1D5, Q71ME6
Gene ID:
  • Human(56624) Summary: Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]
  • Mouse(54447) N-acylsphingosine amidohydrolase 2
  • Rat(114104) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • cow(615837) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • cow(100336736) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • sheep(101121732) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • Horse(100071829) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • domestic cat(101097670) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • dog(486461) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • chicken(423679) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • Zebrafish(493602) N-acylsphingosine amidohydrolase 2
  • naked mole-rat(101709668) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • domestic guinea pig(100728346) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • Domestic Rabbit(100357673) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA061171
Anti-ASAH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU117931
MISSION® esiRNA, targeting human ASAH2, ASAH2B,
Species
human
EHU005221
MISSION® esiRNA, targeting human ASAH2,
Species
human
EMU001181
MISSION® esiRNA, targeting mouse Asah2,
Species
mouse