Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

SMB00080

Sigma-Aldrich

Swertiamarin

≥95% (LC/MS-ELSD)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C16H22O10
CAS Number:
17388-39-5
Molecular Weight:
374.34
MDL number:
MFCD07783984
UNSPSC Code:
12352205
PubChem Substance ID:
329824758
NACRES:
NA.25

Assay

≥95% (LC/MS-ELSD)

form

solid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](O[C@@H]2OC=C3C(=O)OCC[C@@]3(O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C16H22O10/c1-2-7-14(24-6-8-13(21)23-4-3-16(7,8)22)26-15-12(20)11(19)10(18)9(5-17)25-15/h2,6-7,9-12,14-15,17-20,22H,1,3-5H2/t7-,9+,10+,11-,12+,14-,15-,16+/m0/s1

InChI key

HEYZWPRKKUGDCR-QBXMEVCASA-N

General description

Natural product derived from plant source.

Biochem/physiol Actions

Swertiamarin has shown potential as antiatherogenic agent by inhibiting HMG-CoA reductase activity in high cholesterol fed rats. The high cholesterol fed rats treated with Swertiamarin showed prevention of increased serum total cholesterol, triglycerides, LDLs and VLDLs.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 4

1 of 4

Loganin analytical standard

Supelco

36483

Loganin

Mangiferin Mangifera indica

Sigma-Aldrich

M3547

Mangiferin Mangifera indica

Mangiferin analytical standard

Supelco

06279

Mangiferin

Benzene ACS reagent, ≥99.0%

Sigma-Aldrich

319953

Benzene

Shengguo Zhao et al.
Biomedical chromatography : BMC, 18(1), 10-15 (2004-02-12)
Micellar electrokinetic electrophoresis was employed to determine two active components, gentiopicroside (GE) and swertiamarin (SW) in one Tibetan preparation medicine named shiweilongdankeli, two Tibetan herbal medicines named Gentiana rhodantha and Gentiana kitag and three other Chinese Gentiana medicines named Gentiana
Jaishree Vaijanathappa et al.
Planta medica, 75(1), 12-17 (2008-11-14)
Swertiamarin, a secoiridoid isolated from the ethyl acetate extract of Enicostemma axillare, was evaluated for antiedematogenic activity using carrageenan-, formalin-, and histamine-induced paw edema methods in rats. In the carrageenan-induced method, the percentages of edema inhibition obtained after 5 h
Kangping Xu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 34(11), 1384-1389 (2009-09-24)
To develop an HPLC method for the quantification of six active components in three species (Swertia davidi, S. nervosa and S. mussotii) . The determination was performed on a Hypersil BDS colunm (4. 6 mm x 200 mm, 5 microm).
P Alam et al.
Natural product research, 25(1), 17-25 (2011-01-18)
A high-performance thin layer chromatographic densitometric method for the analysis of swertiamarin in 60% methanolic extract of Enicostemma littorale and commercial formulations has been developed and validated in this study. Swertiamarin was separated on aluminium-backed silica gel 60 F₂₅₄ plates
Chang Jun et al.
Biomedical chromatography : BMC, 22(2), 191-195 (2007-09-14)
When cultivated with Aspergillus niger, swertiamarin, an important drug, is rapidly transformed into erythrocentaurin and (5Z)-5-ethylidene-8-hydroxy-3,4,5,6,7,8-hexahydro-1H-pyrano[3,4-c]pyridin-1-one (M(1)), a new compound with high anti-inflammatory activity. A simple and rapid HPLC method for simultaneous determination of swertiamarin and its two metabolites in
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service