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Key Documents

131601P

Avanti

L-α-Phosphatidylcholine

95% (Egg), Avanti Polar Lipids, Powder

Synonym(s):

L-α-phosphatidylcholine (95%) (Egg, Chicken)

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About This Item

CAS Number:
UNSPSC Code:
12352211
NACRES:
NA.25

product name

Egg PC (95%), Avanti Research - A Croda Brand

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (131601P-1g)
pkg of 10 × 1 g (131601P-10g)
pkg of 5 × 1 g (131601P-5g)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

phospholipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

InChI key

WTJKGGKOPKCXLL-VYOBOKEXSA-N

General description

l-α-phosphatidylcholine constitutes 20% of the total phospholipids in chicken egg. It has palmitic acid (16:0) and oleic acid (18:1) in at sn-1 and sn-2 positions, respectively.
Egg PC (95%) is a mixture of 16 to 22 carbon atoms long acyl chain containing multiple double bonds. Major portion (98%) of phospholipid contains a single saturated and unsaturated chain.
Egg PC is a further purification of Total Egg Extract. This Natural Lipid is a mixture, and the structure shown above is only representative of one possible structure present in the product. Refer to chart for average fatty acid distribution.

Application

Egg PC (95%) has been used for the reconstitution of purified Kv1.3 into liposomes.
Egg PC (95%) has been used in the synthesis of high-density lipoprotein (HDL) based nanoparticle for nerve growth factor (NGF) encapsulation. It has also been used in the proteoliposome preparation.

Biochem/physiol Actions

Egg PC in its saturated form favors inhibition of cholesterol absorption. It is used in lipid preparation and liposomes for biophysical studies. Egg PC contributes cardiovascular disease (CVD) risk by acting as a substrate for microbes leading to of trimethylamine N-oxide (TMAO) synthesis.

Packaging

125 mL Amber Wide Mouth Screw Cap Glass Bottle (131601P-5g)
250 mL Amber Wide Mouth Screw Cap Glass Bottle (131601P-10g)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (131601P-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A multiplatform strategy for the discovery of conventional monoclonal antibodies that inhibit the voltage-gated potassium channel Kv1. 3
Bednenko J, et al.
MAbs, 10(4), 636-650 (2018)
Structure of Outward-Facing PglK and Molecular Dynamics of Lipid-Linked Oligosaccharide Recognition and Translocation
Perez C, et al.
Structure (2019)
Preparation and characterization of novel hdl-mimicking nanoparticles for nerve growth factor encapsulation
Zhu, Jing and Dong, Xiaowei
Journal of Visualized Experiments, (123), e55584-e55584 (2008)
Effects of Cholesterol Concentrations on Egg-phosphatidylcholine-Dihexadecyl-phosphate Liposomes Studied by CW ESR and FT-ESEEM Spectroscopy
Mirosavljevic K and Noethig-Laslo V
Croatica Chemica Acta. Arhiv Za Kemiju, 81(4), 631-636 (2008)
Characterization of interactions of eggPC lipid structures with different biomolecules
Chahar FC, et al.
Chemistry and Physics of Lipids, 210, 60-69 (2018)

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