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Merck

Coenzyme Q10: a therapy for hypertension and statin-induced myalgia?

Cleveland Clinic journal of medicine (2010-07-06)
Marcia Wyman, Mandy Leonard, Thomas Morledge
ABSTRACT

Some small clinical trials seem to show that coenzyme Q10 supplements can be used to lower blood pressure and to treat or prevent myalgia caused by hydroxymethylglutaryl coenzyme A reductase inhibitors (statins). However, larger trials are needed to determine if they are truly effective for these purposes. The authors examine the evidence and also discuss issues such as bioavailability, elimination, safety, and cost.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Coenzyme Q10, ≥98% (HPLC)
USP
Ubidecarenone, United States Pharmacopeia (USP) Reference Standard
USP
Ubidecarenone for System Suitability, United States Pharmacopeia (USP) Reference Standard
Supelco
Coenzyme Q10, analytical standard
Ubidecarenone, European Pharmacopoeia (EP) Reference Standard
Ubidecarenone for system suitability, European Pharmacopoeia (EP) Reference Standard