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  • Two cases of vaginitis caused by itraconazole-resistant Saccharomyces cerevisiae and a review of recently published studies.

Two cases of vaginitis caused by itraconazole-resistant Saccharomyces cerevisiae and a review of recently published studies.

Mycopathologia (2008-04-30)
Vincenzo Savini, Chiara Catavitello, Assunta Manna, Marzia Talia, Fabio Febbo, Andrea Balbinot, Francesco D'Antonio, Giovanni Di Bonaventura, Claudio Celentano, Marco Liberati, Raffaele Piccolomini, Domenico D'Antonio
ABSTRACT

Genitourinary infections caused by non-Candida yeasts are uncommon, and especially due to Saccharomyces cerevisiae. We describe the cases of two adult females with vulvovaginal infections caused by itraconazole-resistant S. cerevisiae who made a full recovery after oral fluconazole therapy. We also provide a concise review of recently published studies on this topic.

MATERIALS
Product Number
Brand
Product Description

Supelco
Itraconazole solution, 2.0 mg/mL (Methanol with 1% 1M HCl), ampule of 1 mL, certified reference material, Cerilliant®
Sigma-Aldrich
Itraconazole, ≥98% (HPLC)
Itraconazole for system suitability, European Pharmacopoeia (EP) Reference Standard
Itraconazole, European Pharmacopoeia (EP) Reference Standard