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  • Kinetic model of oxidation catalyzed by xanthine oxidase-the final enzyme in degradation of purine nucleosides and nucleotides.

Kinetic model of oxidation catalyzed by xanthine oxidase-the final enzyme in degradation of purine nucleosides and nucleotides.

Nucleosides, nucleotides & nucleic acids (2005-10-27)
Kinga Banach, Elzbieta Bojarska, Zygmunt Kazimierczuk, Lucyna Magnowska, Agnieszka Bzowska
ABSTRACT

A new kinetic model is presented for analysis of experimental data of oxidation process catalyzed by milk xanthine oxidase. The kinetics for two substrates, xanthine and its analog 2-chloroadenine, in a broad pH range (5.8-9.0) are best described by an equation which is a rational function of degree 2:3 and 2:2, respectively.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
2-Chloroadenine, 96%
Cladribine impurity C, European Pharmacopoeia (EP) Reference Standard