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Key Documents

H43415

Sigma-Aldrich

4-Hydroxy-6-methyl-2-pyrone

98%

Synonym(s):

3,5-Dihydroxysorbic acid δ-lactone

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About This Item

Empirical Formula (Hill Notation):
C6H6O3
CAS Number:
Molecular Weight:
126.11
Beilstein:
113815
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

mp

188-190 °C (dec.) (lit.)

SMILES string

CC1=CC(O)=CC(=O)O1

InChI

1S/C6H6O3/c1-4-2-5(7)3-6(8)9-4/h2-3,7H,1H3

InChI key

NSYSSMYQPLSPOD-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Irreversible inactivation of chicken liver fatty acid synthetase by its substrates acetyl and malonyl CoA. Effect of temperature and NADP n fatty acid and triacetic acid lactone synthesis.
K R Srinivasan et al.
Biochemical and biophysical research communications, 99(3), 920-927 (1981-04-15)
Synthesis of acetoacetyl-CoA by bovine mammary fatty acid synthase.
S Ghayourmanesh et al.
FEBS letters, 132(2), 231-234 (1981-09-28)
J B Spencer et al.
The Biochemical journal, 288 ( Pt 3), 839-846 (1992-12-15)
6-Methylsalicylic acid synthase has been isolated in homogeneous form from Penicillium patulum grown in liquid culture from a spore inoculum. The enzyme is highly susceptible to proteolytic degradation in vivo and in vitro, but may be stabilized during purification by
Dongming Xie et al.
Biotechnology and bioengineering, 93(4), 727-736 (2005-10-26)
Native g2ps1-encoded 2-pyrone synthase (2-PS) from Gerbera hybrida, a mutant Brevibacterium ammoniagenes fatty acid synthase B (FAS-B) and two different mutants of Penicillium patulum 6-methylsalycilic acid synthase (6-MSAS) are examined to identify the best enzyme to recruit for the microbial
Wenjuan Zha et al.
Journal of the American Chemical Society, 126(14), 4534-4535 (2004-04-09)
Metabolic pathway engineering is a powerful tool to synthesize structurally diverse and complex chemicals via genetic manipulation of multistep catalytic systems involved in cell metabolism. Here, we report the rational design of a fatty acid biosynthetic pathway, Brevibacterium ammoniagenes fatty

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