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137456

Sigma-Aldrich

2-Ethyl-2-oxazoline

≥99%

Synonym(s):

2-Ethyl-4,5-dihydrooxazole, 2-Ethyloxazoline

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About This Item

Empirical Formula (Hill Notation):
C5H9NO
CAS Number:
10431-98-8
Molecular Weight:
99.13
EC Number:
233-912-4
MDL number:
MFCD00005302
UNSPSC Code:
12352100
PubChem Substance ID:
24848326
NACRES:
NA.22

Quality Level

100

Assay

≥99%

form

liquid

refractive index

n20/D 1.437 (lit.)

bp

128.4 °C (lit.)

mp

−62 °C (lit.)

density

0.982 g/mL at 25 °C (lit.)

SMILES string

CCC1=NCCO1

InChI

1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3

InChI key

NYEZZYQZRQDLEH-UHFFFAOYSA-N

General description

2-Ethyl-2-oxazoline undergoes cationic ring opening graft polymerization using tosylated cellulose nanowhisker as macroinitiator.

Application

2-Ethyl-2-oxazoline (EtOx) was used in synthesis of block copolymers of EtOx and styrene by cationic ring-opening polymerization and atom transfer radical polymerization.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Warning

Hazard Statements

H226,H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

84.2 °F - closed cup

Flash Point(C)

29 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Poly(2-methyl-2-oxazoline), hydroxy terminated average Mn 5,000, PDI <1.3

Sigma-Aldrich

795283

Poly(2-methyl-2-oxazoline), hydroxy terminated

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Synthesis of poly (2-ethyl-2-oxazoline)-b-poly (styrene) copolymers via a dual initiator route combining cationic ring-opening polymerization and atom transfer radical polymerization.
Becer CR, et al.
Macromolecules, 41(14), 5210-5215 (2008)
Věra Mazánková et al.
Polymers, 12(11) (2020-11-19)
Polyoxazoline thin coatings were deposited on glass substrates using atmospheric pressure plasma polymerization from 2-ethyl-2-oxazoline vapours. The plasma polymerization was performed in dielectric barrier discharge burning in nitrogen at atmospheric pressure. The thin films stable in aqueous environments were obtained
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 136, 104941-104941 (2019-05-29)
SN-38 is the active metabolite of irinotecan, an FDA-approved chemotherapeutic agent indicated for colorectal carcinoma, which would not be clinically applicable due to its very poorly soluble and hydrolytic degradation properties. To overcome these limitations, it was proposed to conjugate
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