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  • Naturally occurring limonene to cinnamyl-type gamma-butyrolactone substituted aldol condensation derivatives as antioxidant compounds.

Naturally occurring limonene to cinnamyl-type gamma-butyrolactone substituted aldol condensation derivatives as antioxidant compounds.

Natural product communications (2012-10-19)
Pushpinder Kaur, Pralay Das, Abha Chaudhary, Bikram Singh
ABSTRACT

A method has been developed for the synthesis of gamma-butyrolactone substituted cinnamyl type Aldol condensation products under milder proline and triethylamine basic conditions. The antioxidant activity of all the synthesized compounds was assessed using three different assays. The cinnamyl type derivatives of gamma-butyrolactone bearing an -OH group in the benzene ring exhibited excellent antioxidant activity.

MATERIALS
Product Number
Brand
Product Description

Supelco
(R)-(+)-Limonene, analytical standard
Sigma-Aldrich
(R)-(+)-Limonene, 97%
Sigma-Aldrich
(R)-(+)-Limonene, technical, ~90% (sum of enantiomers, GC)
Sigma-Aldrich
(S)-(−)-Limonene, 96%
Supelco
(S)-(−)-Limonene, analytical standard
Sigma-Aldrich
(S)-(−)-Limonene, ≥95%, FG