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S7257

Supelco

Sulfamethoxypyridazine

analytical standard

Synonym(s):

N1-(6-Methoxypyridazin-3-yl)sulfanilamide

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About This Item

Empirical Formula (Hill Notation):
C11H12N4O3S
CAS Number:
80-35-3
Molecular Weight:
280.30
Beilstein:
277076
MDL number:
MFCD00057372
UNSPSC Code:
41116107
PubChem Substance ID:
329824580
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1

InChI

1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)

InChI key

VLYWMPOKSSWJAL-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLBR4321V
MKBR2073V
SLBD6074V
050H0647
095F0657

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Sulfadiazine 99.0-101.0%

Sigma-Aldrich

S8626

Sulfadiazine

S K Garg et al.
Veterinary research, 28(1), 101-104 (1997-01-01)
The pharmacokinetics of sulfamethoxypyridazine (SMP) was investigated in goats after a single intramuscular (im) or subcutaneous (sc) administration (100 mg/kg body weight). The biological half lives of SMP following im and sc administration were found to be 11.0 and 13.7
P Bustamante et al.
The Journal of pharmacy and pharmacology, 47(7), 550-555 (1995-07-01)
The solubility of sulphamethoxypyridazine was measured at several temperatures in mixtures of water:ethanol and ethanol:ethyl acetate. Sulphamethoxypyridazine was chosen as a model drug to compare the solvation effects of proton donor-proton acceptor (water and ethanol) and proton acceptor (ethyl acetate)
J E Gach et al.
Journal of the American Academy of Dermatology, 53(2 Suppl 1), S101-S104 (2005-07-16)
Pemphigoid nodularis is a chronic and uncommon variant of bullous pemphigoid. The condition is characterized by the presence of prurigo nodularis-like lesions, possible history of blistering, and immunohistochemical findings of bullous pemphigoid. These patients are often unresponsive to conventional therapy
W T Hughes et al.
Antimicrobial agents and chemotherapy, 40(4), 962-965 (1996-04-01)
A remarkably high rate of adverse events is associated with the use of trimethoprim-sulfamethoxazole in patients with human immunodeficiency virus type 1 infection. We examined the efficacies of sulfonamides alone in the prevention of Pneumocystis carinii pneumonitis, with the assumption
D Bonazzi et al.
Farmaco (Societa chimica italiana : 1989), 49(6), 381-386 (1994-06-01)
Derivative and difference spectrophotometric methods are described for the direct simultaneous analysis of combinations of Trimethoprim with sulfonamide drugs (sulfadiazine, sulfamethoxazole, sulfamethoxypyridazine) in commercial dosage forms. The more advantageous approach (derivative and difference mode) is suggested for each binary mixture.
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