Skip to Content
Merck
All Photos(3)

Key Documents

View All Documentation

06975

Sigma-Aldrich

tert-Butyl 4-aminobenzoate

≥98.0% (NT)

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C11H15NO2
CAS Number:
18144-47-3
Molecular Weight:
193.24
Beilstein:
2803178
MDL number:
MFCD00665790
UNSPSC Code:
12352209
PubChem Substance ID:
329748316
NACRES:
NA.22

Assay

≥98.0% (NT)

reaction suitability

reaction type: solution phase peptide synthesis

color

white to almost white

mp

108-110 °C

application(s)

peptide synthesis

SMILES string

CC(C)(C)OC(=O)c1ccc(N)cc1

InChI

1S/C11H15NO2/c1-11(2,3)14-10(13)8-4-6-9(12)7-5-8/h4-7H,12H2,1-3H3

InChI key

KYORUZMJUKHKFS-UHFFFAOYSA-N

Related Categories

Other Notes

Building block for the synthesis of antifolates, important as tumor cell inhibitors

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000370697
0000370697
0000217523
0000217523
0000142637

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

G.M.F. Visset et al.
Journal of Medicinal Chemistry, 35, 659-659 (1992)
L F Hennequin et al.
Journal of medicinal chemistry, 39(3), 695-704 (1996-02-02)
Modification of the potent thymidylate synthase (TS) inhibitor 1-[[N-[4-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-N- prop-2-ynylamino]benzoyl]amino]methyl]-3-nitrobenzene (4a) has led to the synthesis of quinazolinone antifolates bearing functionalized alkyl substituents at C2. A general synthetic route was developed which involved coupling the appropriate 1-[[N-[4-(alkylamino)benzoyl)amino]methyl]-3-nitrobenzene 20-22 with a

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service