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MAB1950Z

Sigma-Aldrich

Anti-Integrin α2 Antibody, clone P1E6, azide free

clone P1E6, Chemicon®, from mouse

Synonym(s):

CD49b, MAB1950

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

P1E6, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable

isotype

IgG1

suitability

not suitable for immunohistochemistry (Paraffin)

NCBI accession no.

NM_002203.3

UniProt accession no.

P17301

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGA2(3673)

Specificity

Recognizes Alpha 2 integrin.

Application

Suitable for use in attachment inhibition assays using fibroblasts, epithelial cells, endothelial cells, and non-activated platelets on collagen types I, III, IV, VI and laminin.

Suitable for immunofluorescence using fresh frozen or acetone fixed tissues. Not recommended for traditional formalin fixed paraffin embedded tissues.

Final working dilutions must be determined by end user.
This Anti-Integrin α2 Antibody, clone P1E6, azide free is validated for use in IC, IH, FUNC for the detection of Integrin α2.

Physical form

Format: Purified
Protein A Purified mouse immunoglobulin in 0.01 M phosphate buffered saline, pH 7.1, with no preservatives.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Integrin ?5?1 facilitates cancer cell invasion through enhanced contractile forces.
Mierke, CT; Frey, B; Fellner, M; Herrmann, M; Fabry, B
Journal of Cell Science null
Richard A Que et al.
Journal of biomedical materials research. Part A, 106(5), 1363-1372 (2018-01-18)
Adhesion to the microenvironment profoundly affects stem cell functions, including proliferation and differentiation, and understanding the interaction of stem cells with the microenvironment is important for controlling their behavior. In this study, we investigated the effects of the integrin binding
Li Pan et al.
International journal of molecular sciences, 19(2) (2018-02-22)
Soybean agglutinin (SBA), is a non-fiber carbohydrate related protein and a major anti-nutritional factor. Integrins, transmembrane glycoproteins, are involved in many biological processes. Although recent work suggested that integrins are involved in SBA-induced cell-cycle alterations, no comprehensive study has reported
Santoshi Muppala et al.
Arteriosclerosis, thrombosis, and vascular biology, 35(9), 1975-1986 (2015-07-04)
Thrombospondin-4 (TSP-4) is 1 of the 5 members of the thrombospondin protein family. TSP-1 and TSP-2 are potent antiangiogenic proteins. However, angiogenic properties of the 3 other TSPs, which do not contain the domains associated with the antiangiogeneic activity of
Miriam Becker et al.
Journal of virology, 97(10), e0077023-e0077023 (2023-10-12)
Enteric adenoviruses have historically been difficult to grow in cell culture, which has resulted in lack of knowledge of host factors and pathways required for infection of these medically relevant viruses. Previous studies in non-intestinal cell lines showed slow infection
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