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858120P

Avanti

14:0 Lyso PG

Avanti Research™ - A Croda Brand

Synonym(s):

1-tetradecanoyl-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); PG(14:0/0:0); 110710

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About This Item

Empirical Formula (Hill Notation):
C20H40O9PNa
CAS Number:
326495-21-0
Molecular Weight:
478.49
UNSPSC Code:
51191904
NACRES:
NA.25

description

1-myristoyl-2-hydroxy-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

Assay

>99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC)

form

powder

packaging

pkg of 1 × 1 g (858120P-1g)
pkg of 1 × 500 mg (858120P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

General description

14:0 Lyso phosphoglycerol is a lyso-phospholipid detergent. Lyso-phospholipids are non bilayer forming lipids, that are synthesized in γ-proteobacteria. They are minimally found in very minute amounts in normal bacterial membranes.

Application

14:0 Lyso PG has been used as a standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions.

Biochem/physiol Actions

Lyso phosphoglycerol (Lyso PG) acts as a substrate for lysophosphatidylglycerol acyltransferase 1 (LPGAT1) for the synthesis of phosphoglycerol.

Packaging

20 mL Clear Glass Screw Cap Vial (858120P-1g)
20 mL Clear Glass Screw Cap Vial (858120P-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Description
Pricing

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Christine Lockey et al.
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The glycopeptide antibiotic vancomycin has been widely used to treat infections of Gram-positive bacteria including Clostridium difficile and methicillin-resistant Staphylococcus aureus. However, since its introduction, high level vancomycin resistance has emerged. The genes responsible require the action of the two-component
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Chadwick A, et al.
Protein Expression and Purification, 107, 35-42 (2015)
Substrate selectivity of lysophospholipid transporter LplT involved in membrane phospholipid remodeling in Escherichia coli
Lin Y, et al.
The Journal of Biological Chemistry, 291(5), 2136-2149 (2016)
Comprehensive untargeted lipidomic analysis using core-shell C30 particle column and high field orbitrap mass spectrometer
Narvaez-Rivas M and Zhang Q
Journal of Chromatography A, 1440, 123-134 (2016)
Hideo Shindou et al.
The Journal of biological chemistry, 284(1), 1-5 (2008-08-23)
Cell membranes contain several classes of glycerophospholipids, which have numerous structural and functional roles in the cells. Polyunsaturated fatty acids, including arachidonic acid and eicosapentaenoic acid, are located at the sn-2 (but not sn-1)-position of glycerophospholipids in an asymmetrical manner.
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