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300112S

Avanti

Dox-NP™ (2mL vial)

Avanti Research™ - A Croda Brand

Synonym(s):

Dox-NP™ (2mL vial)

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.25

description

Dox-NP™ (Liposomal Encapsulated Doxorubicin)
frozen liposomal suspension (buffer - 10% w/w sucrose, 10 mM histidine ~pH 6.5)

Assay

>99% (HPLC/MS)

form

dispersion

packaging

pkg of 1 × 2 mL (300112S-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand

application(s)

advanced drug delivery

shipped in

dry ice

storage temp.

−20°C

Application

Dox-NP™(2mL vial) is suitable for use:
  • in ultraviolet-visible (UV-vis) spectra, cryo-transmission electron microscopy (cryo-TEM) and analytical ultracentrifuge experiments
  • in transmission electron microscopy (TEM) imaging studies
  • to analyse the effect of gold nanoparticle loaded liposomes on anti-tumor and cytotoxicity properties of DOX-NP on Ehrlich tumor

Biochem/physiol Actions

Dox-NP™ (doxorubicin loaded nanoparticles) is a liposomal drug encapsulating doxorubicin. This encapsulation reduces the side effects of doxorubicin and increases the effective local dose.

Packaging

10 mL amber serum vial (300112S-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
Dox-NP is a trademark of Avanti Polar Lipids, LLC

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H340,H350

Hazard Classifications

Carc. 1B - Muta. 1B

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Analytical ultracentrifugation for analysis of doxorubicin loaded liposomes
Mehn D, et al.
International Journal of Pharmaceutics, 523(1), 320-326 (2017)
Enhanced Ehrlich tumor inhibition using DOX-NP and gold nanoparticles loaded liposomes
Mady MM, et al.
Pakistan Journal of Pharmaceutical Sciences, 1(28), 2321-2325 (2015)
Transmission electron microscopy as a tool for the characterization of soft materials: application and interpretation
Franken LE, et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 4(5), 1600476-1600476 (2017)

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