- Cobalt-Catalyzed ortho-C-H Functionalization/Alkyne Annulation of Benzylamine Derivatives: Access to Dihydroisoquinolines.
Cobalt-Catalyzed ortho-C-H Functionalization/Alkyne Annulation of Benzylamine Derivatives: Access to Dihydroisoquinolines.
Chemistry (Weinheim an der Bergstrasse, Germany) (2017-06-22)
Ángel Manu Martínez, Nuria Rodríguez, Ramón Gómez-Arrayás, Juan C Carretero
PMID28636162
要旨
A practical picolinamide-directed C-H functionalization/alkyne annulation of benzylamine derivatives enabling access to the previously elusive 1,4-dihydroisoquinoline skeleton was developed using molecular O
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