Detection of Atherosclerotic Inflammation by

Detection of Atherosclerotic Inflammation by

Journal of the American College of Cardiology (2017-04-08)

Jason M Tarkin, Francis R Joshi, Nicholas R Evans, Mohammed M Chowdhury, Nichola L Figg, Aarti V Shah, Lakshi T Starks, Abel Martin-Garrido, Roido Manavaki, Emma Yu, Rhoda E Kuc, Luigi Grassi, Roman Kreuzhuber, Myrto A Kostadima, Mattia Frontini, Peter J Kirkpatrick, Patrick A Coughlin, Deepa Gopalan, Tim D Fryer, John R Buscombe, Ashley M Groves, Willem H Ouwehand, Martin R Bennett, Elizabeth A Warburton, Anthony P Davenport, James H F Rudd

PMID28385306

要旨

Inflammation drives atherosclerotic plaque rupture. Although inflammation can be measured using fluorine-18-labeled fluorodeoxyglucose positron emission tomography ([ This study tested the efficacy of gallium-68-labeled DOTATATE ( We confirmed Target SSTR2 gene expression occurred exclusively in "proinflammatory" M1 macrophages, specific We validated