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Antigen targeting to dendritic cells combined with transient regulatory T cell inhibition results in long-term tumor regression.

Antigen targeting to dendritic cells combined with transient regulatory T cell inhibition results in long-term tumor regression.

Oncoimmunology (2015-09-26)

Wendy Wj Unger, Christian T Mayer, Steef Engels, Christina Hesse, Maurizio Perdicchio, Franz Puttur, Ingeborg Streng-Ouwehand, Manja Litjens, Hakan Kalay, Luciana Berod, Tim Sparwasser, Yvette van Kooyk

要旨

Therapeutic vaccinations against cancer are still largely ineffective. Major caveats are inefficient delivery of tumor antigens to dendritic cells (DCs) and excessive immune suppression by

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ホルボール 12-ミリスタート 13-アセタート, ≥99% (TLC), film or powder

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DAPI, for nucleic acid staining

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ホルボール 12-ミリスタート 13-アセタート, for use in molecular biology applications, ≥99% (HPLC)

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Isopropyl alcohol, ≥99.7%, FCC, FG

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2-プロパノール, BioUltra, for molecular biology, ≥99.5% (GC)

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ブレフェルジンA, from Penicillium brefeldianum, ≥99% (HPLC and TLC)

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2-プロパノール, electronic grade, 99.999% trace metals basis

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ホルボール 12-ミリスタート 13-アセタート, synthetic, ≥98.0% (TLC)

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ブレフェルジンA, ≥99% (HPLC and TLC), BioXtra, for molecular biology

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2-プロパノール, JIS special grade, ≥99.5%

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2-プロパノール, anhydrous, 99.5%

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2-プロパノール, for molecular biology, BioReagent, ≥99.5%

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ブレフェルジンA, from Penicillium brefeldianum, Ready Made Solution, 10 mg/mL in DMSO

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2-プロパノール, SAJ first grade, ≥99.0%

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2-プロパノール, suitable for HPLC

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2-プロパノール, ACS reagent, ≥99.5%

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エチジウムブロミドモノアジド, ≥95% (HPLC), solid

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2-プロパノール, HPLC Plus, for HPLC, GC, and residue analysis, 99.9%, poly coated bottles