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Enantiospecific total synthesis of (-)-bengamide E.

Enantiospecific total synthesis of (-)-bengamide E.

Chemistry, an Asian journal (2012-12-05)

Prashant K Metri, Raphael Schiess, Kavirayani R Prasad

要旨

Total synthesis of the polyhydroxy caprolactam amide natural product, bengamide E, is accomplished starting from tartaric acid. Key reactions in the synthesis include desymmetrization of the bis(dimethylamide) unit of tartaric acid, Zn(BH(4))(2)-mediated anti-selective reduction, and a Horner-Wadsworth-Emmons olefination.

材料

製品番号

ブランド

製品内容

Sigma-Aldrich

ε-カプロラクタム, 99%

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L(+)-酒石酸, ACS reagent, ≥99.5%

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D(−)-酒石酸, ReagentPlus^®, 99%

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DL-酒石酸, ReagentPlus^®, 99%

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L(+)-酒石酸, ≥99.7%, FCC, FG

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L(+)-酒石酸, ≥99.5%

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DL-酒石酸, ≥99%

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L(+)-酒石酸, puriss. p.a., reag. ISO, 99.5-101.0% (calc. to the dried substance)

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L(+)-酒石酸, anhydrous, free-flowing, Redi-Dri^™, ACS reagent, ≥99.5%

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D(−)-酒石酸, puriss., unnatural form, ≥99.0% (T)

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L(+)-酒石酸, JIS special grade, ≥99.5%

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L(+)-酒石酸, BioXtra

Supelco

L(+)-酒石酸, certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

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L(+)-酒石酸, SAJ first grade, ≥99.5%

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L(+)-酒石酸, AR, ≥99%