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Merck

"One-pot" multicomponent approach to indolizines and pyrido[1,2-a]indoles.

Organic letters (2011-04-23)
Huajian Zhu, Joachim Stöckigt, Yongping Yu, Hongbin Zou
要旨

A new synthetic protocol for efficient and regiospecifc assembly of indolizines and pyrido[1,2-a]indoles by coupling of substituted methyl bromides and alkynes with corresponding pyrrole-2-carboxaldehyde and 1H-indole-2-carboxaldehyde has been developed. Additionally, a possible mechanism for the reaction is proposed.

材料
製品番号
ブランド
製品内容

Sigma-Aldrich
ピロール-2-カルボキシアルデヒド, 98%