コンテンツへスキップ
Merck

Synthesis of platinum(II) chiral tetraamine coordination complexes.

Journal of combinatorial chemistry (2006-09-12)
Adel Nefzi, Cornelia E Hoesl, Clemencia Pinilla, George B Kauffman, Gerald M Maggiora, Elena Pasquale, Richard A Houghten
要旨

The individual and combinatorial syntheses of individual as well as a mixture-based diversity of 195 112 platinum(II) coordination complexes of chiral tetraamines are described. The use of both solid-phase synthesis and solution phase follow-on approaches were found to best afford the title compounds.