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Merck

Concise asymmetric total synthesis of obolactone.

The Journal of organic chemistry (2006-03-25)
Jiyong Zhang, Yang Li, Wenkuan Wang, Xuegong She, Xinfu Pan
要旨

The first efficient asymmetric synthesis of obolactone 1 has been accomplished in 11 steps and with a 15% overall yield in which Brown's enantioselective allylation reactions and ring-closing metathesis reaction are key steps.

材料
製品番号
ブランド
製品内容

Sigma-Aldrich
4-フェニル-3-ブテン-2-オン, 99%
Sigma-Aldrich
ベンジリデンアセトン, ≥98%, FG
Sigma-Aldrich
trans-4-フェニル-3-ブテン-2-オン, ≥99%