- Lactone-free ginkgolides via regioselective DIBAL-H reduction.
Lactone-free ginkgolides via regioselective DIBAL-H reduction.
Organic & biomolecular chemistry (2005-09-21)
Hideki Ishii, Sergei V Dzyuba, Koji Nakanishi
PMID16172680
要旨
The lactone rings of ginkgolide A are converted into corresponding tetrahydrofuran moieties via DIBAL-H reduction followed by deoxygenation of the formed lactols with Et3SiH-BF3.Et2O to produce a series of lactone-free ginkgolides.