SRP8030

Fn14 (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

• 別名: FGF-誘導 14
• UNSPSCコード: 51111800
• NACRES: NA.32

特性

• 由来生物: human
• リコンビナント: expressed in HEK 293 cells
• アッセイ: >95% (SDS-PAGE)
• 形状: lyophilized
• 分子量: ~35 kDa by SDS-PAGE
• 包装: pkg of 50 μg
• 保管条件: avoid repeated freeze/thaw cycles
• 不純物: <0.1 EU/μg endotoxin, tested
• 色: white
• UniProtアクセッション番号: Q9NP84
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... TNFRSF12A(51330)

詳細

詳細

TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK-Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke.

物理的形状

凍結乾燥品(PBS)。

再構成

Reconstitute with 50 μL deionized water.

その他情報

The extracellular region of human FN14 (aa 28-75) is fused at the C-terminus to the Fc portion of human IgG1.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable