SRP6553

CIRBP/Cold-inducible RNA-binding protein human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• 別名: A18HNRNP, CIRP
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• 由来生物: human
• リコンビナント: expressed in E. coli
• アッセイ: ≥90% (SDS-PAGE)
• 形状: lyophilized
• 分子量: 20.5 kDa
• 包装: pkg of 1 mg; pkg of 20 μg
• 不純物: ≤1 EU/μg endotoxin (LAL test)
• UniProtアクセッション番号: Q14011
• 輸送温度: wet ice
• 保管温度: −70°C
• 遺伝子情報: human ... CIRBP(1153)

詳細

詳細

CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator. CIRBP can bind the 3′untranslated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly.

物理的形状

Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.25 M Imidazole, 20% glycerol.

再構成

Detailed reconstitution instructions are sent along with the product

安全性情報

• ピクトグラム: GHS08,GHS07
• シグナルワード: Danger
• 危険有害性情報: H315,H319,H360D
• 注意書き: P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• 危険有害性の分類: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable