SML0617

A-804598

≥98% (HPLC)

• 別名: N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine
• 実験式（ヒル表記法）: C₁₉H₁₇N₅
• CAS番号: 1125758-85-1
• 分子量: 315.37
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: white to beige
• 溶解性: DMSO: 10 mg/mL, clear
• 保管温度: 2-8°C
• InChI: 1S/C19H17N5/c1-14(15-7-3-2-4-8-15)23-19(22-13-20)24-18-11-5-10-17-16(18)9-6-12-21-17/h2-12,14H,1H3,(H2,22,23,24)/t14-/m0/s1
• InChI Key: PQYCRDPLPKGSME-AWEZNQCLSA-N

詳細

生物化学的／生理学的作用

A-804598 is a P2X7 selective, competitive antagonist. In competition assays, the IC₅₀s for human, rat and mouse channels are 11, 10 and 9 nM, respectively.

特徴および利点

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H301
• 注意書き: P264 - P270 - P301 + P310 - P405 - P501
• 危険有害性の分類: Acute Tox. 3 Oral
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable